The taxonomy of several species of Trichopilia sect. Trichopilia with small, mostly white flowers is discussed. Two new species, T. endresiana and T. tubella, are described and illustrated. Both new species are closely allied to T. turrialbae, but can be distinguished by the smaller flowers and the lateral keels of the lip subequally branched to clasp the small osmophores in acute angles, and by the lip distinctly longer than the sepals and the smooth area of the osmophores, respectively.